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Intestinal iron absorption is regulated, to a large extent, at the basolateral membrane of enterocytes [59, 248].It is at this location that ferroportin-1 (Fpn1; AKA solute carrier family 40 member 1) fulfills its function as the sole cellular efflux protein for ionic iron, shuttling apically absorbed iron to the circulation, where it is oxidized and loaded onto transferrin (TF) [].

(PDF) "Pumping iron"—how macrophages handle iron at the ...

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This article is part of the special issue on macrophages in tissue homeostasis in Pflügers Archiv - European Journal of Physiology BPumping iron^-how macrophages handle iron at the systemic, microenvironmental, and cellular levels Manfred Nairz 0 1 2 Igor Theurl 0 1 2 Filip K. Swirski 0 1 2 Guenter Weiss 0 1 2 0 Department of Internal Medicine VI, Infectious Diseases, Immunology ...

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The pharmacoepigenetic apparatus is integrated by gene clusters of different categories, including (i) pathogenic genes involved in disease pathogenesis, (ii) mechanistic genes encoding components of the epigenetic machinery serving as targets for epigenetic drugs, (iii) metabolic genes associated with the metabolism of drugs (phase I and phase II enzymatic reactions), (iv) transporter genes ...

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FEELS hails from capital weird (aka Providence, Rhode Island, home of AS220) and is comprised of Anthony Ferreira and Ted James (Paper Eagles). Ted was also recently remixed Daddy's "Love In The Old Days" which was subsequently used for a video directed by James Franco and featured experimental film icon Kenneth Anger.Anthony has been involved in AS220 since 2008, and is also associated with …